Alzheimer's disease in Brazilian elderly has a relation with homocysteine but not with MTHFR polymorphisms
نویسندگان
چکیده
منابع مشابه
Alzheimer's disease in Brazilian elderly has a relation with homocysteine but not with MTHFR polymorphisms.
OBJECTIVE To investigate the association between total plasma homocysteine concentration, C677T and A1298C polymorphisms in MTHFR gene and Alzheimer's disease (AD) development. METHOD Forty-three patients with probable (63%) and possible (37%) AD and 50 non-demented controls were evaluated. Groups did not differ as to gender, age, scholar years, diabetes, alcohol and coffee intake and physica...
متن کاملAssociation of CCR2 Gene but not CCR5 Gene Polymorphisms with Alzheimer’s Disease
Chemokines participate in the regulation of immune and inflammatory responses by interacting with their specific receptors on related immune and inflammatory cells such as B-lymphocytes, T-lymphocytes and antigen-presenting cells. Chemokines and their receptors are therefore considered to mediate inflammation and tissue damage in autoimmune disorders. The recent studies have revealed the genoty...
متن کاملAssociation of MTHFR C677T polymorphism with loneliness but not depression in cognitively normal elderly males.
Methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism is involved in folate and homocysteine metabolism, and has been associated with geriatric disorders, including dementia and late-life depression. The present work aimed to investigate the effect of MTHFR C677T polymorphism on the presence of depression and loneliness in cognitively normal male subjects. A total of 323 cognitively no...
متن کاملassociation of ccr2 gene but not ccr5 gene polymorphisms with alzheimer’s disease
chemokines participate in the regulation of immune and inflammatory responses by interacting with their specific receptors on related immune and inflammatory cells such as b-lymphocytes, t-lymphocytes and antigen-presenting cells. chemokines and their receptors are therefore considered to mediate inflammation and tissue damage in autoimmune disorders. the recent studies have revealed the genoty...
متن کاملAssociation of acute ischemic stroke with the MTHFR C677T polymorphism but not with NOS3 gene polymorphisms in a Singapore population.
BACKGROUND AND PURPOSE The association of polymorphisms in the nitric oxide synthase 3 (NOS3) gene (T-786C, variable number tandem repeats 4A/B/C, and G894T) and in the methylenetetrahydrofolate reductase (MTHFR) gene (C677T) with acute ischemic stroke have been reported. METHODS First-time onset acute ischemic stroke patients (n = 120) and controls (n = 207) with no past history of stroke we...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Arquivos de Neuro-Psiquiatria
سال: 2006
ISSN: 0004-282X
DOI: 10.1590/s0004-282x2006000600010